Question of the Week

Question :

Posted On : 08 Mar 2007

I have a four year child with consolidation of lung. It suggest tuberculous but child has early hepatitis {SGPT - 57}. I want to start AKT. What are your guidelines?

Expert Answer :

No expert answer available.

Answer Discussion :

DR.NIZAM

FIVEFOLD RISE OF SGPT VALUES ARE SIGNIFICANT.
WITH THIS VALUE YOU CAN START ATT.
HRZ ARE MORE HEPATOTXIC.SM AND EMB ARE NON HEPATOTOXIC.

18 years ago

mammen puliyel

start full dose 4 drug att as the jaundice is not att induced

18 years ago

kantakumari

akt can be started but w-frequent monitoring of liver enzymes,you need not discontinue until enzyme levels are 3 times elevated,if so withdraw them and slowly reintroduce once enzyme levels come to nl...

18 years ago

pediatriconcall

An increase in 2-3 fold in the liver enzymes is not a deterrent to giving standard first line anti TB drugs. However one must monitor the child when on ATT and if the liver enzymes rise further then the drugs need to be changed.

18 years ago

dpupadhyayin

2 line non hepatotoxic drug

18 years ago

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