Jaundice, skin rash and anemia

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Jaundice, skin rash and anemia

Author: Pediatric Oncall

Question
This girl presented with jaundice, skin lesions and anemia of 15 days duration. She was diagnosed to have epilepsy and was started on Phenytoin 2 months ago.

This girl presented with jaundice, skin lesions and anemia of 15 days duration. She was diagnosed to have epilepsy and was started on <a class='interlink' href='/drugs/anti-epileptics/phenytoin/81/872'>Phenytoin</a> 2 months ago. <br></table>

What is the diagnosis?

Answer Discussion :

D

drahmed fawzy

1

Steven Johnson syndrome

5 years ago

M

Mohamed Faisal

0

hemolytic anemia

5 years ago

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Answer 1

Phenytoin hypersensitivity syndrome (PHS). It is a rare, and important entity characterized by rash, fever, lymphadenopathy, leukocytosis with atypical lymphocytes, eosinophilia and associated hepatitis. Treatment consists of stopping Phenytoin and giving steroids to control the hypersensitivity.

Jaundice, skin rash and anemia

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