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Question :

Posted On : 18 Apr 2005

Why Familial fatal Insomnia, Gerstman Straussler sheinker syndrome ,dementia patients should not donate blood?

Expert Answer :

No expert answer available.

Answer Discussion :

Pravin G. Patel

All these are prion diseases.{subgroup of creutzfeldt-jakob disease i.e.CJK }There is defect in protein named prion.
Prion aggragates in nervous tissue and provoke rapid neurodegeneration .
Prion diseases are non infectious in usual way.Although they are transmisible in certain circumstances.

As unlike bacteria and viruses prion are not inactivated by heat, UV light or other standard sterilization procedure,these patients should not donate blood to minimise potensial risk

20 years ago

pediatriconcall

Human prion diseases or transmissible spongiform encephalopathies {TSE} are rare transmissible diseases affecting the central nervous system. Genetic TSE are seen with Gerstmann-Straussler-Scheinker and Fatal Familial Insomnia. Hence blood donation is contraindicated as they may be transmitted through blood donation.

20 years ago

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