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Posted On : 01 Dec 2012

when do we start a child on leukotriene antagonists, dose and precautions to be taken when we start on them

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Answer Discussion :

R

Rolando Lezama

0

hepatic eosinphilic infiltration
churg straus syndrome
no for acute crisis
4,5 6

12 years ago

Answer 1

Use of Leukotrienes inhibitors in Children.
• In Children with Virus infection triggered wheeze with history of internisttent asthma.
• In persistent mild asthma as a controller alternate to low dose inhaled steroids.
• Add on therapy to inhaled steroids to reduce the dose of steroids.
• In Children of asthma with Allergic Rhinitis.
• In Children with exercise induced asthma.
Dosage
Dosage is age related to age.
• 6 months to 2 Yrs : 4 mg oral granules daily at night.
• 2 Years to 5 Yrs : 4 mg chewable tablet daily at night.
• 2 Years to 5 yrs : 5 mg chewable tablet daily at night.
• 15 Years and over : 10 mg film coated tablet daily at night.

Precautions:
• No safety concerns have been demonstrated in young children
• Zileuton has been associated with liver toxicity.
not in use in India. Please monitor Liver functions.
• Rarely Churg-Strauss Syndrome {vesculitis}, May be due to reduction of steroids when the dose is decreased with the addition of Montelukast.

Dr. H. Paramesh MD, FAAP {USA}, FIAP, FIAMS, FIAA, FICAAI
Medical Director, Pulmonologist
Lakeside Medical Center and Hospital
No.33, 4, Meanee Avene Road
Near Ulsoor Lake, Bangalore – 560 042
Karnataka, India
Ph: 080 – 2566738, 25366723, 253610823
Mobile: 91 9845022689
Fax: 080 – 25303677, 25304276
Email: dr_paramesh1@yahoo,com

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