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Posted On : 06 Jan 2010

What is the role of Midazolam in neonatal seizure

Expert Answer :

Answer Discussion :

I

iman elayadi

0

drug of choice

15 years ago

A

ali azzawi

0

decrease frequency of seizre bouts

15 years ago

M

MOHD ALKHATIM

0

effective for short seizures

15 years ago

A

ANITA SINGH

0

for acute control of seizure

15 years ago

J

Jasbir S Chugh

0

Midazolam has shown good results in controlling refractory seizures non-responsive to common drugs like Phenobarbiton and Phenytoin . The use of this drug for Neonatal seizures improves later Neuro-development of the child.

15 years ago

Answer 1

Midazolam is a sedation similar to Diazepam except for the respiratory depression seen in Diazepam. Benzodiazepines are NOT anti-convulsants - Midazolam is used in Neonatal seizures to sedate the baby if the convulsions are distressing for the parents - but they don`t STOP convulsions as such - especially you can seee EEG seizures. Hence you need to consider an appropriate anti-convulsants for the seizure control.

Dr R Kishore Kumar
Consultant Neonatalogist

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