Question of the Week

Question :

Posted On : 19 Nov 2005

The half life of Dexamethasone is 24 hours, then why we are giving it six hourly in treatment of bacterial meningitis?

Expert Answer :

No expert answer available.

Answer Discussion :

meenal lakshmanan

to reduce intra cranial hypertension and reduc ethe risk from fibrous reaction post inflammation

19 years ago

DR.SYED KASHIF ABBAS

BECAUSE PERTICULAR LEVEL IS REQUIRED TO INHIBIT SYNTHESIS OF CYTOKINE

19 years ago

Enrique Finetti

because the minimal concentracio must be stable

19 years ago

Dr P.R. Kulkarni

DEXA IS USED IN MENINGITIS AS ANTIINFLAMMATORY AGENT. PEAK PLASMA LEVELS IT TAKES TIME YO RAISE.DURATION OF ACTION MAY BE 24 HR BUT ANTIINFLAMMATORY PEAK PLASMA LEVELS LAST FOR 6 HRS. SO GIVEN 6 HRLY.

19 years ago

dr.s-halloush

to get higher serum level as the course it self is short {3-4}days so ot decrese the effect of cell lysis of the invasive bacteria

19 years ago

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