Question of the Week

Question

Question :

Posted On : 21 Oct 2012

Can Deflazocort b used in place of wysolone in Nephrotic Syndrome_?If so whats the regime_?

Expert Answer :

Answer Discussion :

P

Pravin G Patel

0

I have used in 4-5 Nephrotic patients. Initialy with proteinuria I used Wysolone ,Once urine is clear, as maintenance I used Deflazacort,I have not yet experiance to start with Deflazocort however 1 mg of Wysolone is equivalent to 1.2 mg Deflazocort

12 years ago

S

sanjeev khera

0

yes, in the same regime as wysolone

12 years ago

P

pushpa latha

0

yes 5mg of prdnisolone =6mg of deflazocort

12 years ago

V

vrdas

0

there have been no recommendationa on the usage of delazacort ...its better not used.

12 years ago

M

Manoharan

0

yes.same regime

12 years ago

Answer 1

There are no randomized controlled studies between Prednisolone and Deflazacort in management of new onset nephrotic syndrome. So, the current view is to continue use of Prednisolone as per the German protocol. For long term safety benfits, Deflazacort is superior to Prednisolone {specifically on bones and eyes}, and can be used in place of Prednisolone once the child is in complete remission after a relapse. 5 mg of Prednisolone is equivalent to 6 mg of Deflazacort. The cost factor of Deflazacort has to be considered before prescribing {~ Re 1 per 1 mg}

Question of the Week

Home

Partner Sites