Question of the Week

Question :

Posted On : 03 Aug 2005

Why staphylococcal scalded skin syndrome mostly affects infants? What is its pathology?

Expert Answer :

No expert answer available.

Answer Discussion :

dr nilesh gothi

because immunity is low

19 years ago

prathiba pai

it is mediated by exfoliative toxins A and B produced by hematogenous spread of staph.usually antitoxins are produced against these.in the absence of these antitoxin antibodies and decreased renal clearance of exfoliative toxins in infants makes them more prone

19 years ago

neeta kevlani

because of lack of Ig A

19 years ago

Wafa A. Bashir

Reduced immunity. Production of toxins and free radicals by the organism

19 years ago

pediatriconcall

Staphylococcal scalded skin syndrome {SSSS} almost always occurs in infants, and immunosuppressed adults or adults with renal failure. Infants have an immature immune system.

Pathology: Group II coagulase-positive staphylococci, usually phage type 71 and often resistant to penicillin, elaborate exfoliatin {also called epidermolysin}, an epidermolytic toxin that splits off the upper part of the epidermis just beneath the granular cell layer.

19 years ago

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