Question of the Week

Question :
Posted On : 01 Dec 2017
IN A CASE OF PUO if fever is due to ANY auto immune
disease THEN WHAT COULD BE THE POSSIBLE PRESENTATION AND INVESTIGATION FINDING.I SAW A CASE ONE MONTH BACK WHO WAS HAVING PROLONG FEVER HIS WIDAL WAS POSITIVE O TITRE 1, 360 BUT HE DIDI NOT RESPONDED TO INJ CEFTRIXONE,INJ Chloramphenicol ETC.NOW I WAS TOLD HE WAS DIAGOSED AS AUTO IMMUNE DISEASE.AT THAT TIME HE DID NOT HAVE ANT RASHES OR JOINT PAIN ETC.I HAVE NOT SEEN THE REPORT OF THAT PT .I JUST WANTED TO KNOW
THE POSSIBLE CAUSE OF AUTOIMMUNE DISORDER WHICH PRESENT AS PROLONG FEVER AND WIDAL POSITIVE.BY FACIES OF PATIENT IT APPEARS HE WAS GIVEN STEROIDS
3
Expert Answer :
Systemic onset JIA may just present as fever. Rash or joint involvement may occur later. Also in case of prolonged fever, one must rule out hemophagocytosis and also malignancy. Widal may be non specific marker often elevated due to hypergammaglobulinemia due to autoiimmune disease.
Answer Discussion :
D
dr.prashant ram
Profile
in that case detailed history and examination needed....it may be an HEMOPHAGOCYTIC HISTIOCYTOSIS(HLH)...
7 years ago
S
Saddy Vankalas
Profile
start naproxen
7 years ago
A
abdul rafe
Profile
ANA LEVELS
7 years ago




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