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Question :

Posted On : 09 Dec 2011

for parasitic index 4plus with p. falciparum can i use alfa beta arteether and Quinine both together with TMP_?

Expert Answer :

Answer Discussion :

S

sree harsha

0

alfa beta arteether is not recommended in children according to latest guidelines. one can use artemesin combination therapy{ACT} consisting of artesunateplus sulafadoxine pyrimethamine combination{kindly let us know whether malaria is severe}

13 years ago

A

A R Chaudhari

0

No ,either quinine or artemisinine with Sulpha pyrimehamine would be sufficient.

13 years ago

D

david camarena enriquez

0

Not because are antagonist

13 years ago

S

Shreeshail V Benekane

0

no, this combination is not indicated in recomendations,

13 years ago

R

RAHUL TANDON

0

yes we can give both medicine

13 years ago

Answer 1

3 anti-malarials shall not be used together. The choice of anti-malarial and the route of administration depends on the severity of the disease {severe malaria in this situation} and the local drug sensitivity pattern. However, for a patient with severe malaria, the general reccomendation is to use IV Quinine infusion {IM if IV is not possible} till the patient can take orally. Thereafter, switch to oral Quinine to complete seven days of therapy.

Alternatively, a single dose of SP {if sensitive} or a combination of Artemether, Lumefantrine can be used to complete the course following injectable therapy.

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