ISSN - 0973-0958

Pediatric Oncall Journal View Article

Impact of A Urine Culture Follow-Up Program On The Reduction of Inappropriate Antibiotic Use In Children
Mariana Poppe1, Francisco Branco Caetano2, Rodrigo Sousa1, Paulo Oom1.
1Department of Pediatrics, Hospital Beatriz Ângelo, Loures, Portugal,
2Hospital Dona Estefânia, Lisboa, Portugal.
Abstract
Objectives: We aim to characterize the follow-up management of urine culture results from a pediatric emergency department and thus quantify the unnecessary days of antibiotic therapy avoided due to this approach.
Materials and Methods: We conducted a retrospective study in a hospital in the metropolitan area of Lisbon. Data was collected through a dataset referring to pediatric patients who visited the emergency department and had a urine culture performed in 2021. We analyzed the rate of continuation, start, suspension and switch of antibiotics after acknowledgment of urine culture results.
Results and Discussion: 851 children and adolescents were included in the study. 71.5% of patients who were prescribed an antibiotic in the emergency department and had a negative urine culture were contacted to discontinue the antibiotic. 494 days of inappropriate antibiotic treatment were avoided, corresponding to a 44.5% reduction in the number of antibiotic treatment days for these patients.
Conclusion: Our follow-up management led to a reduction of unnecessary antibiotic therapy days, thus leading to better patient care and potentially contributing towards a decreased spread of antibiotic resistance. Limitations of the study include the lack of records of the patient’s medical history or clinical outcomes after discontinuation of antibiotic therapy.
Why this article important?
We believe that this manuscript is appropriate for publication in the Pediatric Oncall Journal and consider it to be interesting for your readers, as it approaches the importance of implementing antimicrobial stewardship strategies in pediatric settings. Similar follow-up methods could be implemented in other hospitals with minimal added resources and with clear benefits for patients.
Summary of article
We wish to submit an original research article entitled “Impact of a urine culture follow-up program on the reduction of inappropriate antibiotic use in children” for consideration by the Pediatric Oncall Journal. In this paper, we report the impact of an antimicrobial stewardship program, through the review of urine cultures results, on the reduction of days of unnecessary antibiotic treatment in a pediatric department. We gathered information in the year of 2021 regarding 858 children and adolescents and consider this study to be relevant in an era of antibiotic overprescription and spread of antibiotic resistance. We confirm that this work is original and has not been published elsewhere, nor is it currently under consideration for publication in any other journal. All authors made a significant contribution to this study and have read and approved the final version of the manuscript. None of the authors have conflicts of interest to disclose.

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