Question of the Week

Question :
Posted On : 01 Feb 2008
Why Quinine if given alongwith artimisnin compound is harmful ?
4
Expert Answer :
No expert answer available.
Answer Discussion :
M
MOHAMMAD NASIM
Profile
IT WL CAUSE AGRANULOCYTOSIS
17 years ago
S
shilpa
Profile
BOTH CAUSE QT prolongation
17 years ago
P
pediatriconcall
Profile
Both quinine and artemisin compounds have the same side effects and thus may have an additive effect on the adverse effects. Also there is no added advantage by giving both the drugs together for treatment of malaria as both are short acting drugs and now the recommendation is to give one short acting drug with one long acting drug to prevent relapse of malaria. The combinations thus recommended are artesunate Plus mefloquine or pyrimethamine sulfamethoxazle and artemether with lumfantrine. The combination with quinine and clindamycin or doxycycline.
17 years ago
R
ramadevi
Profile
drug interaction
17 years ago




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