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Posted On : 04 Aug 2018

inhaled corticosteroid by its nongenomic action influence the cationic transport across the mitochondrial membrane produces immediate effect of reducing mucosal edema and muscle spasm. Hence it is beneficial and recomended in the treatment of Croup.By the same mechanism theoreticaly it must be beneficial in treatment of acute asthma.so why is it not helpful in acute asthma_?

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Answer Discussion :

D

D Manjunath

0

in acute asthma needs immediate brochodilatation ie beta agonist not steroids

6 years ago

O

Osama Mustafa Simsaa

0

I think the action occurs after 2 hours

6 years ago

K

Kuwar Ashit

0

in asthma there bronchoconstriction along with edema. for immediate relief there needs to be bronchodilatation.so inhaled steroids are not useful for acute asthma

6 years ago

Answer 1

Inhaled corticosteroids are used in acute exacerbation of asthma too if the child is already on inhaled therapy and dose may be increased. However for status asthmaticus, inhaled steroids would not reach the bronchus due to severe bronchoconstriction and hence systemic steroids are required.

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