Question of the Week

Question :
Posted On : 03 May 2006
4 years female presentd with sudden attack of fever,loose motion. No Family history of favism,or blood transfusion. On examination, GC is good, she has striking pallor,no icterus ,no hepatosplenomegaly,no significant lymphglands. Lab values: HBg 6g Percent, Ret.count 10 Percent ,normocytic hypochromic blood picture and platelet count is normal. There is no hemoglobinuria ,no blood in the stool. What further suggestions to reach diagnosis?
5
Expert Answer :
No expert answer available.
Answer Discussion :
D
Dr Sanwar Agrawal
Profile
look for malaria again.
uncommon causes Autoimmune hemolytic anemia and PNH should also be kept in mind

18 years ago
A
ahmad
Profile
hereditary blood disease in the family?pure red cell anemia
18 years ago
D
DR BHUSHAN SALUNKE
Profile
parvoviral infection
18 years ago
P
pediatriconcall
Profile
Since her retic count is high, one needs to rule out hemolysis be it autoimmune hemolytic anemia, malaria, enzyme defects like pyruvate kinase deficiency. G-6-PD is unlikely as the child is a female child. Also bleeding should be ruled out as in dengue fever or viral hemorrhagic fever.
18 years ago
P
pramod m.kulkarni
Profile
Severe normocytic anemia,reticulocytosis,absence of organomegaly suggest intravascular hemolysis quite likely of acute onset.
sr.billirubin,coomb's test initially,
g6pd-PK assays if needed,should help in further invest.

18 years ago




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