All Grand Rounds

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An infant with seizures with positive human herpes virus 6 on multiplex PCR and positive herpes simplex virus 1 on uniplex PCR - How to interpret?
Ramsha Ansari, Aditi Gupta, Zahabiya Nalwalla, Ira Shah
A 6 month old boy presented in May 2024 with fever, cough and cold for 10 days along with generalized tonic clonic convulsions on day 8 of fever followed by excessive irritability and refusal to feed.....
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Asymptomatic Congenital Parvovirus infection in a neonate born to an asymptomatic mother with Parvovirus infection in the third trimester - Management issues
Zahabiya Nalwalla, Ramsha Ansari, Tsering Yangchen Dirkhipa, Forum Shah, Amol Pawar, Ira Shah
A 29 year old primigravida (G1P1L0A0) was admitted to the hospital following a spontaneous rupture of membrane at 38 weeks of gestation. Antenatal ultrasound (USG) scan at 30+5 weeks of gestation show....
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Cheek cysticercosis - To Treat or Not to Treat
Dhruv Gandhi, Shatakshi Garg, Zahabiya Nalwalla, Balagopal Kurup, Tejas Athalye, Sunita Sharma, Ira Shah
A 14-year-old boy presented with a painless, progressively enlarging right cheek swelling for six months. There was no fever or trauma. He had a mixed dietary pattern. On examination, there was a soli....
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Successful Recovery from HHV-6 Encephalitis in an Immunocompetent Child
Vaidehi Mehta, Suhani Jain, Meenakshi Dey, Ira Shah
A 2-year-old female child presented with a 10 day history of persistent fever and an episode of paroxysmal event on the 1st day of illness. Her family history was unremarkable and vaccinations were up....
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Discordance Between Xpert MTB/RIF Assay and Line Probe Assay- How to Interpret?
Dhruv Gandhi, Aditi Gupta, Zahabiya Nalwalla, Ira Shah
A 2-year-old boy presented with a progressively enlarging painful swelling over the right cheek for 8 days. It was associated with fever. There was no facial trauma, toothache, dysphagia, neck swellin....
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Polymicrobial infection in immunocompromised host - How to manage?
Meenakshi Dey, Suhani Jain, Ira Shah
A 2 year 9 month old male suffering from STAT1 gain of function mutation on whole exome sequencing diagnosed at the age of 6 months in view of recurrent pneumonia presented to us with fever and cough ....
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Discordance between mycobacterial tuberculosis whole genome sequencing and phenotypic drug sensitivity - How to interpret
Meenakshi Dey, Suhani Jain, Ira Shah
A 14-year-old female presented in August with complaints of cough, easy fatiguability, shortness of breath for the past 2-3 months. She also had a 6.5 kg weight loss in the past 8 months and no menstr....
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Hereditary Spherocytosis with splenectomy in a Pregnant Woman - How to manage the immunizations?
Tsering Yangchen Dirkhipa, Suhani Jain, Meenakshi Dey, Ira Shah
A 38 year old female, G3P1L1A1 at 31+4 weeks of gestation with expected date of delivery in February 2024 and a known case of hereditary spherocytosis with splenectomy done 11 years back in 2012 (at 1....
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Interpretation of Cytomegalovirus (CMV) serology
Meenakshi Dey, Suhani Jain, Ira Shah
A 31 year old primigravida at 12 weeks of gestation was referred to us for evaluation based on the results of a TORCH panel. The test indicated that her cytomegalovirus (CMV) IgG level was 280 Au/ml a....
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Nocardiosis in an immunocompromised child with peripherally inserted central catheter - how to treat?
Zahabiya Nalwalla, Tsering Yangchen Dirkhipa, Ira Shah, Venkata Rama Mohan Gollamudi
A 12 year old boy was diagnosed as Non-metastatic Ewing’s sarcoma of left scapula in July 2021. He was receiving chemotherapy and a peripherally inserted central catheter (PICC) line was inserted for ....
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