Paediatric Ovarian Tumours: Appropriate Investigations and Management

 
print
Irina Earnshaw*, James Fraser Horwood**, Edmund Cheesman***, Ross Craigie****
University of Manchester, Manchester, UK*, Royal Manchester Children’s Hospital, Manchester, UK**, Royal Manchester Children’s Hospital, Manchester, UK***, Royal Manchester Children’s Hospital, Manchester, UK****
Email
irina.earnshaw@student.manchester.ac.uk
Aim
The rarity of paediatric ovarian tumours and their incomparability with adult ovarian tumours has made their management an area of uncertainty for many years. Most of these tumours are benign, and have a risk of metachranous disease, so preservation of the affected ovary is preferable. We sought to find under what circumstances this was possible, and how surgeons can guide their decision-making.
Patients & Methods
A pathology database search returned 59 reports of 60 tumours, occurring in 49 patients.
Results
Twenty-five tumours were left-sided, 26 right-sided, 3 bilateral and 3 extra-ovarian metastases. Mean age at presentation was 12.6 ± 3.7 years. Thirty-six (60%) were benign, 3 (5%) were borderline and 20 (33.3%) were malignant, and the majority (78%) were germ cell tumours. Twenty-four percent of ovaries were preserved. The current mean follow-up period is 22 ± 24.5 months, with 18 patients discharged so far. Metachranous disease occurred in 6.1% of patients, and ipsilateral recurrence occurring in 13.3% of preserved ovaries. Two patients have reported reproductive issues.
Conclusion
A number of patients underwent oophorectomy when preservation of the ovary may have been possible. It is recommended that preservation should be attempted in all cases where the tumour is under 10cm and tumour markers are negative. If the tumour markers are negative and the tumour is over 10cm, approach is at the discretion of the surgeon, but preservation of the ovary should be the main goal, with the understanding that a second look operation may be necessary if histology returns a malignancy.
 
How to Cite URL :
Earnshaw I, Horwood F J, Cheesman E, Craigie R.. Available From : http://www.pediatriconcall.com/conference/abstract/36/view/850
ask a doctor
Ask a Doctor
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0