Home
Submit New Manuscript
Manuscripts in Draft (
0
)
Pending Revisions (
0
)
Manuscripts in Review (
0
)
Accepted Manuscripts (
0
)
Rejected Manuscripts (
0
)
Manuscripts in Review (
0
)
Co-Author History (
0
)
Home
Pending Review (
0
)
Expired/Declined (
0
)
Accepted Manuscripts (
0
)
Rejected Manuscripts (
0
)
Menu
Disease
A-Z
Health Topics
Alternative Medicine
Developmental Pediatrics
General Pediatrics
Genetics
Immunodeficiencies
Infectious Diseases
Laboratory Medicine
Neonatology
Nutrition
Pediatric Cardiology
View all Topics
Featured Articles
Diabetic ketoacidosis
Circumcision
Urticaria (hives) and angioedema
Anaphylaxis
Skin allergies
Anal itching
Kids Corner
Health and Knowledge with fun.
Drugs &
Calculators
Medical Calculators
Drug Calculators
Genetic Calculators
Growth Calculators
View all Calcualtors
Drug Index
ACE inhibitor
Alkylating agents
Allergies
View all Drugs
Poisoning Center
Aluminum phosphide
Anti-histaminics
Antidepressants
View all Drugs
Medical Eqipments
Monitors
Pumps
Incubators
View all Equipments
Diagnostic Aid
Get your diffrential
diagnosis.
Consult
& Posts
Ask a Doctor
Diagnostic Dilemma
Question of the Week
Pediatric Blogs
Spot Diagnosis
Grand Rounds
Pedi Poll
Pediatric
Journal
Current Issue
All Issues
Advance Access
About the Journal
Submit Article
Books
& Apps
Book Store
Pediatric Oncall
Medical Calculators
Vaccine Reminder
Pediatric Oncall Journal
Drug Center
Parenting
CME &
Videos
Upcoming Conferences
Conference Abstracts
MCQs
Videos
Vaccine
Reminder
Sign In
Conference Abstract
›
National Medical Students Paediatric Conference (NMSPC) 2014, Brighton, UK
›
Patent Ductus Arteriosus in preterm infants: does it matter if we wait longer to treat?
Patent Ductus Arteriosus in preterm infants: does it matter if we wait longer to treat?
Ashra Omr*
St Georges’ University, London, UK*
Abstract
Background:
Whether to close a patent ductus arteriosus (PDA) and the timing of treatment are common clinical dilemmas for clinicians looking after preterm infants. Many clinicians are less willing to treat and wait for the PDA to close. However, there is a concern that if treatment is required, infants are being treated later in postnatal life which may be less effective.
Aims:
1.To evaluate the impact of timing of treatment on the need for ligation and associated outcomes.
2.To determine the impact of gestational age on need for ligation.
3.To compare outcomes of infants requiring ligation with those where PDA closed medically.
Methods:
Data for 112 babies with treated PDAs between 2007-2013 were collected from the St George’s neonatal database for: intervention used to close the PDA and timing of the intervention. Outcome data was identified for duration of treatment, chronic lung disease (CLD), respiratory support at 36 weeks corrected gestation, home oxygen, mortality, intraventricular hemorrhage, necrotising enterocolitis, and retinopathy of prematurity.
Results:
The likelihood of requiring surgical ligation was higher than medical closure only for infants born at 23 weeks gestation. Of those who underwent ligation, a greater proportion were ventilated at 36 weeks (35% vs 4%, p<0.001) and discharged on home oxygen (62% vs. 28%, p =0.01). Although the likelihood of medical closure was higher when medication was commenced in the first 3 weeks of life, mortality rates were higher the earlier treatment was commenced (numbers however were low). There were no other significant associations found between the interventions, gestational age, clinical outcomes and treatment timing.
Conclusions:
The results support the current concerns expressed in the neonatal medical literature that treatment does little to alter clinical outcomes except in very few selected cases. A symptomatic ‘wait and watch’ approach before offering treatment is warranted.
How to Cite URL :
Omr A.. Available From : http://www.pediatriconcall.com/conference/abstract/33/view/813
Conference Abstract List
Patent Ductus Arteriosus in preterm infants: does it matter if we wait longer to treat?
The Ponseti Method for the Management of CTEV – 10 year Results
Congenital Talipes Equinovarus ‘Clubfoot’ in Zambia: A qualitative study on the influences on treatment-seeking behavior at Beit Cure Hospital, Zambia.
Questionnaire Survey Evaluating Patient Satisfaction on the Provision of Paediatric Anaesthetic Pre-operative Information
Does drinking breast milk as opposed to formula milk have an impact on the cognitive development of a baby?
Ask a Doctor
Book Store
Case Rounds In Pediatric Liver Disorders
Order Now
Recommended for you
Toxic Shock Syndrome
Squint (Strabismus)
Vitamin E
Videos
Decoding Microbiological Mystery
Skin Hemangiomas with Limb Hypertrophy
Abscess Alert! What This Toddler's Bump Revealed | Pediatric Oncall
View All
Spot Diagnosis
Axillary swelling after vaccine
Unusual case of cervical swelling
Neonatal lupus erythematosus - a cause to remember in newborn dermatosis
View All
Pediatric Oncall Journal
Original Article
Characterization of Sleep Patterns and Disturbances in School-Aged Children: A Cross-Sectional Study in an Island Population
Case Reports
MCQ
MCQS ON PEDIATRIC EMERGENCIES
MCQs Set 2
MCQs - Body Fluids and Fluid Therapy
MCQs on Immunization
MCQs in Neonatal Resuscitation
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
X
Sign In
Disease A-Z
Health Topics
Alternative Medicine
Developmental Pediatrics
General Pediatrics
Genetics
Immunodeficiencies
Infectious Diseases
Laboratory Medicine
Neonatology
Nutrition
Pediatric Cardiology
View all topics
Featured Articles
Diabetic ketoacidosis
Circumcision
Urticaria (hives) and angioedema
Anaphylaxis
Skin allergies
Anal itching
Kids Corner
Drugs & Calculators
Medical Calculators
Drug Calculators
Genetic Calculators
Growth Calculators
View all Calculators
Drug Index
ACE inhibitor
Alkylating agents
Allergies
View all Drugs
Poisoning Center
Aluminum phosphide
Anti-histaminics
Antidepressants
View all Drugs
Medical Eqipments
Monitors
Pumps
Incubators
View all Eqipments
Diagnostic Aid
Consult & Posts
Ask a Doctor
Diagnostic Dilemma
Question of the Week
Pediatric Blogs
Spot Diagnosis
Grand Rounds
Pedi Poll
Pediatric Oncall Journal
Current Issue
All Issues
Advance Access
About the Journal
Submit Article
Books & Apps
Book Store
Pediatric Oncall
Medical Calculators
Vaccine Reminder
Pediatric Oncall Journal
Drug Center
Parenting
CME & Videos
Upcoming Conferences
Conference Abstracts
MCQs
Videos
Vaccine Reminder
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0