Hepatitis B Vaccination

Ramsha Ansari
MBBS, Medical Editorial Team, Pediatric Oncall.
First Created: 06/29/2016  Last Updated: 12/27/2023

Patient Education

What is Hepatitis B infection?

Hepatitis B infection is caused by the Hepatitis B virus. Hepatitis B virus attacks the liver and causes further damage. Most people having the virus do not present with any symptoms (carrier state).

Hepatitis B virus can infect the liver and cause short term condition (acute) like Liver Infection. It can persist in the body for a long duration (chronic) and cause Chronic Liver Damage or in some cases, Cancer of the liver.

How is Hepatitis B virus spread?

Hepatitis B virus has various modes of transmission.

  • Most common method is from an infected mother to newborn (vertical transmission).
  • It can spread through infected close contacts by sharing of personal items.
  • It can spread by touching open cuts and sores of an infected individual.
  • Sexual transmission from an infected individual is another mode of transmission.

How is the Hepatitis B Vaccine given?

Hepatitis B vaccine is given intramuscularly.

What is the Schedule for Hepatitis B Vaccination?

1st Dose Hepatitis B-1 (BD) vaccine should be administered within 24 hours of birth.

2nd Dose is administered at 6 weeks in combination with other vaccines.

3rd Dose is administered at 10 weeks in combination with other vaccines.

4th Dose may be administered at 14 weeks in combination with other vaccines.

Is the Hepatitis B vaccine safe to use?

Yes, the Hepatitis B virus is considered safe.

Side effects of Hepatitis B Vaccine?

In some cases, side effects can occur presenting as mild symptoms like low grade fever, soreness near site of injection or mild pain. Majority of the individuals who get the Hepatitis B vaccine do not have any side effects. There are no serious side effects noted to occur by the Hepatitis B virus.

Whom to give?

Hepatitis B vaccine is recommended to be given to all infants and children.

Whom not to give?

Children who had a severe allergic reaction during a previous vaccine dose of Hepatitis B vaccine cannot take the vaccine. Children with severe allergy to any component of the vaccine cannot take the vaccine.


1. Iapindia.org [Internet] IAP Vaccine Information. ACVIP: 2020-2021 Available from: https://iapindia.org/vaccine-information/
2. IAP Immunization Timetable 2020/21: IAP Recommended Vaccines for Routine Use
3. Acvip.org (Internet) Hepatitis B Advisory Committee on Vaccines & Immunization Practices. Available from: https://acvip.org/


Hepatitis B Vaccination Hepatitis B Vaccination https://www.pediatriconcall.com/show_article/default.aspx?main_cat=vaccinology&sub_cat=hepatitis-b-vaccination&url=hepatitis-b-vaccination-patient-education 2023-12-27
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