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Question of the Week
Question :
Posted On :
23 Jun 2006
Any online reference about WHO clinical case definition of HIV in children? Whether case definition issued for adults can be applicable to children also.i.e. 2 major and 2 minor criterias.
2
Expert Answer :
No expert answer available.
Answer Discussion :
M
MANGESH DAMODAR KHANDAVE
0
NO AS THE PROGRRESSIPON PRESENTATION IS NOT SIMILAR TO ADULTS.
18 years ago
P
pediatriconcall
0
At present the WHO disease staging system for HIV Infection and Disease in Children is as follows:
Clinical Stage 1:
Asymptomatic
Persistent generalized lymphadenopathy
Clinical Stage 2:
Hepatosplenomegaly
Papular pruritic eruptions
Seborrhoeic dermatitis
Extensive human papilloma virus infection
Extensive molluscum contagiosum
Fungal nail infections
Recurrent oral ulcerations
Linear gingival erythema {LGE}
Angular cheilitis
Parotid enlargement
Herpes zoster
Recurrent or chronic RTIs {otitis media, otorrhoea, sinusitis}
Clinical Stage 3:
- Conditions where a presumptive diagnosis can be made on the basis of clinical signs or simple investigations:
Moderate unexplained malnutrition not adequately responding to standard therapy
Unexplained persistent diarrhoea {14 days or more }
Unexplained persistent fever {intermittent or constant, for longer than one month}
Oral candidiasis {outside neonatal period }
Oral hairy leukoplakia
Acute necrotizing ulcerative gingivitis-periodontitis
Pulmonary TB
Severe recurrent presumed bacterial pneumonia
- Conditions where confirmatory diagnostic testing is necessary:
Chronic HIV-associated lung disease including brochiectasis
Lymphoid interstitial pneumonitis {LIP}
Unexplained anaemia { Less than 80g-l}, and or neutropenia { Less than 1000-µl} and or thrombocytopenia { Less than 50 000-µl} for more than one month
Clinical Stage 4:
-Conditions where a presumptive diagnosis can be made on the basis of clinical signs or simple investigations
Unexplained severe wasting or severe malnutrition not adequately responding to standard therapy:
Pneumocystis pneumonia
Recurrent severe presumed bacterial infections {e.g. empyema, pyomyositis, bone or joint infection, meningitis, but excluding pneumonia}
Chronic herpes simplex infection, {orolabial or cutaneous of more than one month’s duration}
Extrapulmonary Tuberculosis
Kaposi’s sarcoma
Oesophageal candidiasis
Central nervous system toxoplasmosis {outside the neonatal period}
HIV encephalopathy
- Conditions where confirmatory diagnostic testing is necessary:
CMV infection {CMV retinitis or infection of organs other than liver, spleen or lymph nodes, onset at age one month or more}
Extrapulmonary cryptococcosis including meningitis
Any disseminated endemic mycosis {e.g. extrapulmonary histoplasmosis, coccidiomycosis, penicilliosis}
Cryptosporidiosis
Isosporiasis
Disseminated non-tuberculous mycobacteria infection
Candida of trachea, bronchi or lungs
Visceral herpes simplex infection
Acquired HIV associated rectal fistula
Cerebral or B cell non-Hodgkin lymphoma
Progressive multifocal leukoencephalopathy {PML}
HIV-associated cardiomyopathy or HIV-associated nephropathy
The presumptive diagnosis above is designed for use where access to confirmatory diagnostic testing for HIV infection by means of virological testing {usually nucleic acid testing, NAT} or P24 antigen testing for infants and children aged under 18 months is not readily available.
18 years ago
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Disease A-Z
Health Topics
Developmental Pediatrics
General Pediatrics
Genetics
Immunodeficiencies
Infectious Diseases
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Nutrition
Pediatric Cardiology
Pediatric Dermatology
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Anal itching
Anal fissure
Anaphylaxis
Skin allergies
Circumcision
Urticaria (hives) and angioedema
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