Tavaborole
Mechanism :
Tavaborole is an oxaborole antifungal that inhibits fungal protein synthesis by inhibition of an aminoacyl-transfer ribonucleic acid (tRNA) synthetase (AARS).
Indication :
- Topical treatment of onychomycosis of the toenail(s) due to Trichophyton rubrum and Trichophyton mentagrophytes
Contraindications :
No contraindications.
Dosing :
Topical. Children ≥6 years of age: Apply to affected toenail once daily for 48 weeks.
Adverse Effect :
Ingrown nail, local skin exfoliation, application site erythema.
Interaction :
No known significant interactions.
Hepatic Dose :
No dose adjustment recommended.