Salicylic acid
Mechanism :
It softens and destroys the stratum corneum by increasing endogenous hydration which causes the horny layer of the skin to swell, soften, and then desquamate. At high concentrations, salicylic acid has a caustic effect. It also possesses weak antifungal and antibacterial activity.
Indication :
- Indicated for the treatment of warts, acne, corns and dandruff.
Contraindications :
Hypersensitivity.
Prolonged use or application to large areas (risk for salicylism).
Dosing :
>12 years:
Use 1% Salicylic acid topical onto the acne and cleanse the affected area. Apply two to three times a day.
Adverse Effect :
Allergic reactions with symptoms of swelling of lips, tongue, face with hives and urticaria.
Interaction :
Do not use Salicylic acid topical on abrasive skin surface or with drying soaps, other skin cleansers including alcohol cleansers, abrasives, tinctures, other peeling agents and astringents.
Hepatic Dose :
No dose adjustment recommended.