Magnesium Oxide
Mechanism :
Magnesium oxide is a mineral which acts as a cofactor in several enzymatic reactions and is essential for many metabolic functions.
Indication :
- Dietary supplement
- Antacid
Contraindications :
• Contraindicated in patients with hypersensitivity to drug components
• Use cautiously in patients with renal impairment
• Use cautiously in patients with any neuromuscular disorder
• Use cautiously in patients with myasthenia gravis
• Use cautiously in patients with botulism
• Use cautiously in patients with diverticulitis
• Use cautiously in patients with ulcerative colitis
• Use cautiously in patients with colostomy or ileostomy
Dosing :
Available as: (dosage forms expressed as elemental Mg)
Oral tablet of 241.3 mg, 250 mg, 253 mg, 500 mg
Oral capsule of 250 mg, 400 mg, 500 mg
Dosage: (for dietary supplement)
1-3 years: 80 mg/day orally
4-8 years: 130 mg/day orally
9-13 years: 240 mg/day orally
14-18 years (males): 410 mg/day orally
14-18 years (females): 360 mg/day orally
14-18 years (pregnant females): 400 mg/day orally
Adverse Effect :
Diarrhea, GI irritation.
Lactation :
Drug administration is safe in the course of breastfeeding. It is secreted in breastmilk.
Hepatic Dose :
No dose adjustment required.
Pregnanacy :
Pregnancy category A