Covishield (COVID-19 Vaccine)

Mechanism :

It is produced by viral vector based technology. It is a recombinant chimpanzee adenovirus vector encoding the SARS-CoV-2 Spike (S) glycoprotein. Efficacy reported is 70% to prevent COVID-19 infection and 100% hospitalizations due to COVID-19 vaccine.

Indication :

• For immunisation of individuals ≥18 years old for the prevention of coronavirus disease 2019 (COVID-19).

Contraindications :

Patients with a history of heparin-induced thrombocytopenia and thrombosis (HITT or HIT type 2)

Patients who had major venous and/or arterial thrombosis occurring with thrombocytopenia following vaccination with first dose of COVID-19 vaccine should not receive the second dose. 

Dosing :

Adverse Effect :

Common: Headache, nausea, vomiting, diarrhea, myalgia, arthralgia, injection site pain, tenderness, swelling, erythema, warmth, pruritus, bruising, fatigue, malaise, fever, chills

Uncommon: Lymphadenopathy, anaphylaxis, decreased appetite, dizziness, abdominal pain, pruritis, rash, hyperhidrosis.

Lactation :

Breast milk excretion is not known. It is currently recommended to give in lactating mothers.