Anakinra
Indication :
- Chronic Infantile Neurologic Cutaneous Articular Syndrome (CINCA).
- Safety not established for use in JIA in children.
Dosing :
1-2 mg/kg SC every day. Can increase upto 8 g/kg.
Adverse Effect :
Injection site reaction, headache, vomiting, arthralgia, fever, URI, nausea, diarrhea, neutropenia, hepatitis, hypercholesterolemia, thrombocytopenia.
Hepatic Dose :
No dosage adjustments are recommended.