Modified Leipzig Score

Kayser-Fleischer rings
Serum ceruloplasmin
24-h urinary copper (in the absence of acute hepatitis)
Coomb's-negative hemolytic anemia with liver disease
Mutational analysis
Liver biopsy for histology suggestive of WD
Neurobehavioral symptoms
Typical features on MRI brain
History of Wilson disease in a family member
Result :
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References

Nagral A, Sarma MS, Matthai J, Kukkle PL, Devarbhavi H, Sinha S, Alam S, Bavdekar A, Dhiman RK, Eapen CE, Goyal V, Mohan N, Kandadai RM, Sathiyasekaran M, Poddar U, Sibal A, Sankaranarayanan S, Srivastava A, Thapa BR, Wadia PM, Yachha SK, Dhawan A. Wilson's Disease: Clinical Practice Guidelines of the Indian National Association for Study of the Liver, the Indian Society of Pediatric Gastroenterology, Hepatology and Nutrition, and the Movement Disorders Society of India. J Clin Exp Hepatol. 2019 Jan-Feb;9(1):74-98. doi: 10.1016/j.jceh.2018.08.009. Epub 2018 Sep 3. Erratum in: J Clin Exp Hepatol. 2020 Jan-Feb;10(1):99. PMID: 30765941; PMCID: PMC6363961.

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