Question of the Week

Question :
Posted On : 09 Apr 2011
I have a female patient,13 y old with prolonged fever 1 mo ago,delayed puberty,short stature,no HSM.Abdominal us shows chronic medical renal disease.Urine analysis shows only epithelial cells ,on hematuria,no pyurea.CT brain shows empty sella syvdrome.Levels of FSH,LH are within normal for age .CBC had normal values but neutrophils 72 percentof total WBCs.CT chest shows mediastinal lymphadenopathy.ESR 55,100 in 1st,2nd hours.LDH= 635u, l,-ve Widal,brucella tests.Fever was not controlled despite ttt by ampicillin-cefotax for 2 weeks,no other systemic manifestations .What is your differerntial diagnosis,what other needed investigations_?
2
Expert Answer :
Rule out HIV, TB, systemic onset JIA and other autoimmune diseases. A CT chest and abdomen may help to delineate the lymphnodes and determine if they are TB. ALso rule out UTI. DO a urine culture.
Answer Discussion :
A
ahmed hassan
Profile
caryotyping
lymph node biopsy

13 years ago
P
PRABHU
Profile
thymoma
13 years ago




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