Endrin

It is insoluble in water but soluble in alcohol and kerosene oil. it is bitter to taste. it is commonly used as sprays or dusts diluted with inert clays
Route :
Ingestion
Fatal Dose :
5 to 6gm
Fatal Period :
1 to several hours
Mechanism of action :
It interferes with nerve impulse transmission. CNS is first stimulated and then depressed
Clinical Picture :
• Salivation, nausea , vomiting, abdominal pain
• Hoarseness of voice, coughing, froth at mouth and nose, dyspnoea
• Headache, giddiness, restlessness, hyperirritabilty, dilated pupils, in-cordination, mental confusion, tremors, convulsions
• In non-fatal cases, patient feels well after 24hrs

Treatment :
• Clothing should be removed and skin washed with soap and water
• Gastric lavage
• Animal charcoal
• Cholestyramine : increased the fecal excretionof endrin
• Symptomatic
10/22/2024 10:43:56 Endrin
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