Thrombin
Mechanism :
It is a naturally occurring coagulant, usually used in conditions associated with bleeding, to stop bleeding. It is applied topically for minor bleeds.
Indication :
Contraindications :
Hypersensitivity to product or any component.
Dosing :
May soak in up to 10 mL of absorbable gelatin sponge and then applied on bleeding surface. Do not inject systemically, can lead to intravascular clotting and death.
Severe bleeding:
Concentrations of 1000-2000 units/mL.
Mild/moderate bleeding:
Concentrations of 100 units/mL.
Adverse Effect :
Skin incision pain, nausea with vomiting, immune hypersensitivity reaction, thromboembolic disorder, antibody formation.
Hepatic Dose :
No data available