Magnesium Chloride

Mechanism :

Magnesium chloride acts as a cofactor in several enzymatic reactions involving protein synthesis and carbohydrate metabolism; depresses CNS, blocks peripheral neuromuscular transmission, and produces anticonvulsant effects.

Indication :

• Hypomagnesemia

Contraindications :

• Contraindicated in patients with renal impairment

• Contraindicated in comatose patients

• Contraindicated in patients with significant myocardial disease

• Use cautiously in patients with flushing, sweating and signs of magnesium toxicity on administration

• Use cautiously in patients with history of seizures

• Use cautiously in patients with electrolyte abnormalities

• Use cautiously in patients with toxic megacolon, toxic colitis, ulcerative colitis, intestinal obstruction, GI perforation, gastric retention, ileus

• Use cautiously in patients with risk of arrythmias

• Use cautiously in patients with botulism

Dosing :

Adverse Effect :

Sweating, stupor, flushing, hypothermia, respiratory depression, decrease in blood pressure.

Lactation :

Use cautiously in the course of breastfeeding since it is excreted through breast milk.

Hepatic Dose :

No dose adjustment needed.

Pregnanacy :

Pregnancy category C