Gentian Violet
Synonym :
Crystal Violet
Mechanism :
The main target of gentian violet toxicity in the dark is the mitochondrion. Gentian violet is actively demethylated by liver microsomes from different animals and is reduced to leucogentian violet by intestinal microflora.
Indication :
- Fungal infection – candida, prophylaxis and treatment
- Mouth ulcers
Contraindications :
Not established.
Dosing :
Apply to cover the affected area.
Adverse Effect :
Staining skin and cloth, but if used on ulcerations or open wounds it can cause tattooing.
Interaction :
Not established.
Hepatic Dose :
No dosage adjustments are recommended.