Emapalumab
Mechanism :
Human monoclonal antibody that targets and inhibits interferon-gamma (IFN-gamma).
Indication :
- Hemophagocytic Lymphohistiocytosis (Currently in phase III trial)
Contraindications :
Not known.
Dosing :
1 mg/kg IV infusion along with
dexamethasone once every 3 days for the first 2 weeks, then twice weekly.
Adverse Effect :
Not known.
Interaction :
Not yet specified.
Hepatic Dose :
No dosage adjustments are recommended.
Pediatric Oncall
08/27/2024 07:07:23
08/27/2024 07:07:23
Emapalumab