Mebeverine
Mechanism :
It is a drug that modifies intestinal motility and is used in the treatment of irritable bowel syndrome.
Indication :
Contraindications :
Not to be used in paralytic ileus. Use with caution in those who react showing angioedema, thrombocytopenia and young children.
Dosing :
Safety and efficacy not established in children <18 years
>3 years:
25 mg orally thrice daily
4-8 years:
50 mg orally thrice daily
9-10 years:
100 mg orally thrice daily
10-18 years:
200 mg orally thrice daily
Give 30 min before meals.
Adverse Effect :
Not to be used in paralytic ileus. Use with caution in those who react showing angioedema, thrombocytopenia and young children.
Indigestion or heartburn, constipation, dizziness, insomnia, anorexia, headache, tiredness, bradycardia, maculopapular or urticarial rash and/or itchy skin.
Hepatic Dose :
Use with caution in hepatic impairment although no side effects extensively studied.