Dextrose
Synonym :
Glucose
Mechanism :
This medication is an intravenous (IV) solution used to supply fluids and calories to the body. It is also used as a diluent for other IV medications.
Indication :
- Hypoglycemia in premature infants
- Insulin induced hypoglycemia
- Nutritional support
Contraindications :
Solutions containing dextrose may be contraindicated in patients with known allergy to corn or corn products.
Dehydration.
Dosing :
Hypoglycemia:
Premature infants:
0.1-0.2 g/kg/dose, followed by continuous infusion at the rate of 4-6 mg/kg/min.
Infants:
<6 months:
0.25-0.5 g/kg/dose intravenously, Max: 25 g/dose.
>6 months:
0.5: 1 g/kg/dose intravenously, Max: 25 g/dose.
Adolescents:
10-25 g as 20-50 ml as 50% solution intravenously OR 4-20 g oral dose stat; can be repeated after 15 minutes if hypoglycemia persists.
Adverse Effect :
Local injection site reactions, excessive urination, nausea, hyperosmolar syndrome.
Interaction :
Do not administer concurrently with corticosteroids.
Hepatic Dose :
No dosage adjustments are recommended.