NUTRITION IN CHILDREN
EFFECT OF FORTIFICATION WITH MULTIPLE MICRONUTRIENTS AND N-3 FATTY ACIDS ON GROWTH AND COGNITIVE PERFORMANCE IN INDIAN SCHOOL CHILDREN : THE CHAMPION (CHILDREN'S HEALTH AND MENTAL PERFORMANCE INFLUENCED BY OPTIMAL NUTRITION) STUDY


Source: Am J Clin Nutr. 2009;89:1766-1775.
This study was carried out to determine whether supplementation with higher concentration of multiple Micronutrients [fortification of food with 100% of the recommended daily allowance (RDA) of micronutrients] or lower concentration of multiple micronutrients [fortification of food with 15% of the RDA of micronutrients] was more effective in improving growth and cognitive performance in low income school children aged 6-10 years in Bangalore. This was done as a randomized double-blind controlled trial in 598 children. In addition, children also received 900 mg alpha-linolenic acid + 100 mg docosahexaenoic acid (DHA) or 140 mg of alpha-linolenic acid. These fortified feeds were given for 12 months. All children had a baseline growth and cognitive functions assessed which were then reassessed at the end of 12 months of the food fortification. It was found that children who had received 100% fortification of multiple micronutrients had better growth in height at end of 12 months and better short term memory at end of 6 months of intervention. There was no difference seen in weight and overall cognitive performance though cognitive function improved in both groups.
Thus it was found that supplementation of multiple micronutrients in higher concentration was beneficial to improve height in children and both concentrations of micronutrients were effective in improving cognitive performance.
This study was carried out to determine whether supplementation with higher concentration of multiple Micronutrients [fortification of food with 100% of the recommended daily allowance (RDA) of micronutrients] or lower concentration of multiple micronutrients [fortification of food with 15% of the RDA of micronutrients] was more effective in improving growth and cognitive performance in low income school children aged 6-10 years in Bangalore. This was done as a randomized double-blind controlled trial in 598 children. In addition, children also received 900 mg alpha-linolenic acid + 100 mg docosahexaenoic acid (DHA) or 140 mg of alpha-linolenic acid. These fortified feeds were given for 12 months. All children had a baseline growth and cognitive functions assessed which were then reassessed at the end of 12 months of the food fortification. It was found that children who had received 100% fortification of multiple micronutrients had better growth in height at end of 12 months and better short term memory at end of 6 months of intervention. There was no difference seen in weight and overall cognitive performance though cognitive function improved in both groups.
Thus it was found that supplementation of multiple micronutrients in higher concentration was beneficial to improve height in children and both concentrations of micronutrients were effective in improving cognitive performance.
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