Mixing of Vaccines - Vaccines FAQS

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

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Question
It is advised that Td vaccine containing 2 Lf diphteria toxoid should be administered to children older than 7 years and adults and it unfortunately is not available in India. Can we give instead 0.1 ml of DT containing 25 Lf of diphteria toxoid. Can we mix it with tetanus toxoid and give it? If not then what do we for older children who have missed DPT vaccine. Please answer with references. Thank you.
Answer
Theoretically one mix 0.1 ml of DT vaccine and 0.9 ml of TT vaccine (to make 1 ml and) and give 1/2 the dose of the vaccine in adults. However mixing of vaccines is not recommended by Drug Control of India. Hence one may give the 2 vaccines in reduced doses at different sites. However, ideal would be to wait till dT is available in India. Back to All Questions

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