GRAND ROUNDS AND TEACHING FILES
Wilm`s Tumor


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Clinical Problem:


Ira Shah
Medical Sciences Department, Pediatric Oncall, Mumbai, India

Address for Correspondence: Dr Ira Shah, 1, B Saguna, 271, B St Francis Road, Vile Parle {W}, Mumbai 400056


A 9 month old boy was referred for jaundice. He was diagnosed to have right sided Wilm`s tumor at 6 months of age and underwent right sided nephrectomy. He was subsequently on chemotherapy of vincristine and daptomycin. But since past 1 month he had jaundice and chemotherapy had to be stopped. His bilirubin was 3.7 mg, dl {direct = 1.6 mg, dl}, SGOT = 88 IU, L, SGPT = 42 IU, L, Total proteins = 7.1 gm, dl, albumin = 4.2 gm, dl, alkaline phosphatase = 604 IU, L, GGTP = 59 IU, L.



What is the likely cause of jaundice in this child_?

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