Pulmonary Tuberculosis and Hepatitis

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Clinical Problem:

Ira Shah
Medical Sciences Department, Pediatric Oncall, Mumbai, India

Address for Correspondence: Dr Ira Shah, 1, B Saguna, 271, B St Francis Road, Vile Parle {W}, Mumbai 400056

A 5½ years old girl presented with fever, jaundice and loss of appetite for 4 days. She was antituberculous therapy {ATT} consisting of Isoniazid {H} and Rifampicin {R} for past 10 months of view of pulmonary TB. On examination, she had jaundice, hepatomegaly. Other systems were normal. Her investigations showed:
• Bilirubin = 3.9 mg, dl
• SGOT = 245 IU, L, SGPT = 225 IU, L
• Total proteins = 7.8 gm, dl, albumin of 3.2 gm, dl

What is the cause of hepatitis_?

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