4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
After how many weeks of Anti Tubercular treatment can a child have a clear cytology in his CSF? Question 2) And is it contra-indicated to transfuse blood to a patient in hepatic encephalopathy with severe pallor (clinically) with no active bleeding?
Answer
There are no studies that state the clearance of CSF in TBM. However in few studies, it was found that slower bacterial clearance was observed if M. tuberculosis was resistant to isoniazid and/or streptomycin: resistant organisms were more likely to be cultured from cerebrospinal fluid after 2 to 5 days of treatment than fully sensitive organisms.

Ref:
J Clin Microbiol. 2004 March; 42(3): 996-1002.

There is no need to transfuse blood in a child with pallor if he is not in failure and not actively bleeding.
 
 
 
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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
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Yes, under guidance of an infectious disease expert
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