Latest Recommendation of RNTCP in Children

4th Pediatric Infectious Diseases Conference

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Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katihar...

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	Specialist Answers
Question
Can you please tell me the latest recommendation of RNTCP in children? According to the WHO recommendation 2003, category I & III seem to be the same as per treatment.... which was not so in previous year recommendations. Please opine!
Answer
Category 1 (New sputum smear-positive PTB OR Seriously ill extra-pulmonary TB): The intensive phase consists of Isoniazid, Rifampicin, Pyrazinamide and Ethambutol to be given under direct observation thrice a week on alternate days for 2 months (24 doses). The continuation phase consists of 4 months (18 weeks; 54 doses) of Isoniazid and Rifampicin given thrice a week on alternate days - the first dose of every weekly blister being directly observed. Category II (Re-treatment Cases): 5 drugs for 2 months (including streptomycin) and INH, Rifampicin, Ethambutol and Pyrizinamide for 1 month followed by 5 months of INH Rifampicin and Ethambutol. Category III (Sputum smear-negative and extra-pulmonary TB, not seriously ill): 2 months of INH, Rifampicin and Pyrizamide followed by 4 months of INH and Rifampicin. Continuation phase of treatment in TB meningitis and spinal TB with neurological complications should be given for 6 - 7 months, extending the total duration of treatment to 8 - 9 months. Asymptomatic children under 6 years of age, exposed to an adult with infectious (smearpositive) tuberculosis from within the same household, are to be given 6 months of Isoniazid (5 mg per kg daily) as chemoprophylaxis. Back to All Questions

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