4th Pediatric Infectious Diseases Conference
 
 
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Portal hypertension
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Specialist Answers
Question
Where exactly is the pathological lesion in pre-sinusoidal portal hypertension?
Answer
Since portal pressure is the product of portal blood flow and intrahepatic resistance, any condition causing an increase in flow or resistance will increase portal pressure. Almost all other causes of portal hypertension are mediated predominantly by increasing resistance, although evidence indicates that most high-resistance syndromes are also accompanied by increases in portal venous flow. In many conditions, the cause of the increased resistance is evident: inflammation and fibrosis lead to vascular distortion, architectural disturbance and impingement of the intravascular spaces.
 
 
 
Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
Educational Section
 
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