Pancytopenia With Bone Marrow Suppression

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

Pancytopenia

Clinical Tools

Clinical Vignettes

Diseases & Conditions

Drugs Interaction Calculator

Podcasts

Patient Management Online

Diagnostic Dilemma

Question of the Day

Medical Quiz

Interactives

Ask Queries

SPECIALIST ANSWERS

Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katihar...

Video Podcast

Videos in Medicines

Medical Training Videos

Clinical Video Resource

Videos on Asthma

Audio Cast

Lecture on Pediatrics

Medical Training Audios

Clinical Audio Resources

Audios on Asthma

Mobile (wap)

Staying connected to Pediatric Oncall is now easier with Pediatric Oncall Mobile . You can now download selected content from the latest issue of Pediatric Oncall.

Research Grant

FIND DIAGNOSIS

VACCINE REMINDER

Get the Vaccine Schedule for your child."

	Specialist Answers
Question
Infant 10 months old, presented to me by acute onset of pallor (since 4 days). This infant was treated for chest infection since 7 days by parenteral antibiotic (cefotaxime) but no improvement was seen. At the time he was brought to me, there was severe respiratory distress (grade 3) severe pallor, heart failure (enlarged tender liver, tachy cardia > 200 bpm, slight cardiomegaly by x-ray). CBC revealed pancytopenia and reticulopenia (Hb: 2.1 gm, RBC : 800,000 c./cmm, WBC : 2000 c. /cmm, platelets : 45,000, reticulocytic count (corrected) : 0.1 %) this baby was hospitalized, blood transfusion was given, I V fluids was given, oxygen supplied, antibiotic was administered unasyn and claforan. serial CBC revealed improving in RBC count and leckocytic count. But improving in platelets was slightly delayed. blood culture was not done. what is the possible diagnosis and what further investigation are needed ?? sameh , resident of pediatric Benha university hospital.
Answer
One may need to rule out sepsis, DIC, viral hemorrhagic fever. Since there was pancytopenia with bone marrow suppression (Retic low), other causes such as aplastic anemia, leukemia come into the picture. However, the age of the child and acute presentation would keep these differential diagnosis low on the cards. One may do a d-dimer to rule out DIC. A blood culture Bactec resin would be useful even at this stage to rule out a bacterial sepsis. And ELISA for dengue and leptospira would be useful. Finally if the counts do still remain low, a bone marrow examination to rule out leukemia, hemophagosytosis and aplastic anemia would be useful. Back to All Questions

Diseases & Conditions

Pediatric Oncall Journal

Pediatric Conferences

Ped Tools

Adverse Drug Reactions

Head circumference Calculator

Mid parental height Calculator

Body surface area Calculator

BMR Calculator

Temperature Calculator

Anion gap Calculator

Today's Poll

Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?

No, it should be used only after drug sensitivity report

Yes, under guidance of an infectious disease expert

Vote

Results

Pediatric oncall book store

Partner Sites

Infection in Children

Pedcall

Medical ADRIS

Vaccine Reminder

Pediatric Oncall Journal

Educational Section

Disclaimer:

The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.

Sitemap For Doctor

Sitemap For Parent

Sitemap For Kids