4th Pediatric Infectious Diseases Conference
 
 
Home  Back   ISSN 0973 - 0958
 
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Specialist Answers
Question
Respected sir/madam, does new artimisin derivatives have any role on vivax malaria? Does quinine have any action on vivax malaria?
Answer
For chloroquine-sensitive vivax malaria (i.e. in most places where P. vivax is prevalent) the conventional oral chloroquine dose of 25 mg base/kg bw is well tolerated and effective.
It appears that P. vivax has developed resistance to sulfadoxine-pyrimethamine more rapidly than has P. falciparum, so that artesunate + sulfadoxine-pyrimethamine may not be effective against P. vivax in many areas. There are relatively few data on treatment responses in chloroquine-resistant
vivax malaria. Studies from Indonesia indicate that amodiaquine is efficacious,
and there is some evidence that mefloquine and quinine can also be used. The artemisinin derivatives would also be expected to be highly effective, and artemether-lumefantrine could be an alternative treatment. However, there are insufficient clinical data to confirm this.
 
 
 
Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
Educational Section
 
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