4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
For prevention of mother to infant transmission of HIV various trials are used like THAI, ACTG076 & HIVNET. But few physicians and gynecologist use combination therapy like DUOVIR (zidovidine+lamividine OR these two +stavudine or nevirapine DURING ANTENATAL period.(Of course that is justifiable) I want to know what retroviral drug to be given to infant of HIV positive mothers when various such combinations are used? 2)A request-"Question of the day" is a section where we can read other doctor's answers and opinions and it is definitely nice to know others views. But it will be also useful if you add expert's answer for that particular question. Thanking you Yours sincerely Mangesh.
Answer
Depending on the protocol being followed, one needs to continue the medication in infants. One cannot prescribe the ART in mothers without a set protocol and the objective that one expects from it. There are also reports of mitochondrial toxicity due to perinatal exposure to ART and hence one needs to monitor the child and mother accordingly. However with all regimes it is recommended that zidovudine be continued in the infant up to 6 weeks and a single dose of nevirapine may also be given if required.
Regarding the question of the day, the answers by pediatriconcall are the experts answers.
 
 
 
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Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
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