4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
A 3.5 years male child received 3 blood transfusions between March and May 2002 because of development of severe anemia( Hemoglobin. Ranging 4-5 Gm%).His pre transfusion Hemoglobin electrophoresis showed HbA-76.1%, A2-5.3%, F-5.8%, S-12.8% (Reference lab. Ranbaxy). He does not have splenomegaly and retic is 2% prior to transfusion. Why should a thal. minor and sickle trait combined child should have severe anemia to need Blood Transfusion?
Answer
The report does not seem to fit with the diagnosis as Hb S of 12.8 % does not make sense. It would be worthwhile to repeat the child's electrophoresis once again maybe from a different lab later on. Since the child has already received blood transfusion, electrophoresis of the family can be done in the meantime.
 
 
 
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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
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