PULMONARY INFECTIONS - RADIOLOGY
Last Updated : 1/4/2011
Priya Chudgar
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CHILDHOOD PNEUMONIA

Pneumonia

is the most common cause of childhood illness. Radiographic interpretation is mainly based on technique. Films are best exposed at maximal inspiration with quiet breathing. Films made in expiration or with the patient rotated may lead to an erroneous diagnosis of pneumonia. The presence of a prominent thymus in an infant, breast buds in the pubescent teenager or a long hair braid in a child can simulate pneumonia. Also, obstructive airway problems are on important component of childhood non-bacterial respiratory infections. Inflammatory edema, debris & mucus have profound obstructive effects upon small airways in babies. Also, the collateral air pathways are not as well developed. Thus, obstructive overinflation & atelectasis frequently accompanies pulmonary infection.

Lobar pneumonia & Bronchopneumonia

Lobar pneumoniaBronchopneumonia
It is seen as uniform, homogenous, nonsegmental consolidationIt is initially patchy and later distributed along the airways - thus it is segmental & non-homogenous.
Unifocal in distributionMultifocal in distribution
Mainly involves distal airspaces & spares distal airwaysAirways are affected by bronchiolitis. Inflammatory involvement of airways leads to obstruction, atelectasis & occasionally pneumatocele
Air bronchogram is seenAir bronchogram is not seen
Airways are patent so there is no volume lossVolume Loss is seen
Commonly seen with streptococcal pneumoniaCommonly seen with Staphylococcal aureus pneumonia


Pneumonia - Radiological Features
Though it is difficult to evaluate the organism causing pneumonia, some typical radiological features may suggest the likely etiology:
- Lobar or segmental consolidation & atelectasis are more typical of bacterial infection whereas hyperinflation, bilateral patchy/streaky densities, peribronchial thickening are suggestive of non-bacterial diseases.
- Pneumonia & pleural fluid in a child less than one year indicates staphylococcal infection.
- Hilar/mediastinal lymphadenopathy in conjunction with pulmonary consolidation suggest pulmonary tuberculosis, histoplasmosis, fungal infections.
- Pneumatoceles & classical bronchopneumonic pattern is suggestive of staphylococcal aureus
- Diffuse air trapping with hyperinflation & streaky densities radiating from hila are commonly seen with RSV infection.
- Complete radiographic clearing is the rule in viral infection.

COLLAPSE

Signs of collapse

can be divided as:
-

Lobar

: shift of fissure, crowding of airways, increased opacity.
-

Extralobar

: hemidiaphragm elevation, mediastinal shift, hilar shift/distortion, compensatory hyperinflation, rib approximation.

Different lobes of collapse show different features
Right upper lobe collapse: opacity in right upper lobe with minor fissure at cephalic position & its lateral aspect is higher than medial. Adjacent mediastinal silhouette is effaced.
Right middle lobe collapse: Blurring of sharp right heart border & on lateral view, a triangular opacity with apex at hilum is seen.
Lingular collapse: Left cardiac border is ill-defined.
Lower lobe collapse: Triangular opacity in lower lobe with base on diaphragm. Hilar depression, hyperinflation of upper lobe are associated features.
Left lower lobe collapse: shows a retrocardiac triangular opacity.

Figure 1: Left lower lobe collapse


Figure 2: Right middle lobe collapse with minor effusion


Figure 3: Right upper and lower left lobe collapse


PLEURAL EFFUSION
A small amount of free fluid is usually undetectable on chest radiographs. It collects first under the lower lobe - such subpulmonic effusions are detected by lateral decubitus Chest radiographs. Later, there is blunting of posterior & lateral Costophrenic angles (200 - 500ml of effusion). Then there is homogenous opacification of lower chest.

An empyema is radiologically indistinguishable from an effusion on chest radiograph, but should be suspected if pleural effusion is large, delayed in appearance, distributed unusually or loculated.

Fissural location of free fluid appears sharply marginated, biconvex and has a tail along the fissure.

When in supine position, pleural effusion appears as a hazy opacity. Associated haziness of diaphragmatic margin, blunting of costophrenic angle, thickening of minor fissure & widening of paraspinal interface may be apparent.

Figure 4:Encysted effusion in minor fissure


PNEUMATOCELE
Pneumatoceles are defined as thin-walled air containing cavities. In contrast, an abscess has a thick walled irregular cavity.

There are multiple theories for formation of pneumatocele:

1. A peribronchial abscess forms that communicates with the airway permitting entry of air into this abscess & when exudate clears, there is development of a large thin walled cavity- the pneumatocele. The growth of the pneumatocele occurs because of a ball valve obstruction at the site of perforation of airway into the cavity.

2. The pneumatocele is formed by distension of small bronchioles owing to ball valve effect secondary to bronchial obstruction.

3. Current most favored explanation for pneumatoceles is that they are subpleural collection of air formed by dissection of air from ruptured bronchi or alveoli. The dissection occurs through the interstitium of the lung. On radiographs, pneumatoceles appear as thin walled air containing lesion - they may show air fluid level.

Depending on size, it shows mass effect / mediastinal shift. They usually appear during the first week of pneumonia & almost always are gone within 6 weeks. The pneumatocele occurs when child is getting better & its presence does not denote any dire prognostic consequences. Approximately 10% of pneumatocele rupture & cause pneumothorax.

Figure 5: Giant Pneumatocele


PNEUMOTHORAX
The

diagnosis

of even small quantity of air in pleural cavity (1ml) can be made with good quality radiographs. When seen on erect radiographs, pleural air rises to the lung apex & depending on amount of air, ipsilateral lung becomes transradiant. Rarely, expiratory/decubitus films may help to confirm the diagnosis. In supine position, pleural air rises & collects anteriorly, particularly medially & basally. When pleural space is partly obliterated, a pneumothorax may be loculated. It must be differentiated from other loculated transradiancy like cysts, bullae, pneumatoceles. CT may help in doubtful case. When fluid accompanies a pneumothorax, air fluid level is more eye-catching.

Figure: Pyopneumothorax


TUBERCULOSIS
In a developing country like ours, tuberculosis may have broad spectrum of manifestations ranging from consolidation, lymphadenopathy or miliary shadows. The disease is acquired by inhalation from other infected persons. It may be widespread with meningitis or diffuse pulmonary involvement - may appear radiographically as widespread alveolar infiltrates or as miliary nodules.

Primary complex may manifest a small area of peripheral consolidation (Ghon focus) with a lymph node. Apicoposterior segment of an upper lobe or apical segment of a lower lobe commonly shows consolidation.

Pleural effusion & lymphadenopathy are common associated finding.

Hilar, paratracheal lymph nodes are commonly involved. Though adenopathy is infrequently seen with bacterial/viral infection, histoplasmosis may be a differential diagnosis. Rarely obstructive overinflation of a lobe may be caused by extrinsic bronchial compression by adjacent TB lymph node or endobronchial extension of infection.

Miliary opacities range from 1-2 mm. They are diffuse & of soft tissue density.

Silicosis, berylliosis, sarcoidosis & rarely metastasis cause miliary opacities. Thus, a pnemonia with lymphadenopathy or miliary shadows should cause suspicion or tuberculosis.

Figure: Miliary TB


Figure: Pneumonia with hilum enlarged


Figure 9: Paratracheal hilar lymph node


REPEATED NON-RESOLVING PNEUMONIA
Frequent pneumonia in a child should raise suspicion of any congenital anatomical/functional pulmonary abnormality or immunocompromised status. Even after adequate therapy, these pneumonias fail to be cured. Then correlation with serial radiographs is essential.

Repeated RTI are known to occur with heart diseases, cystic fibrosis, asthma, repeated aspirations due to gastro-oesophageal reflux, collagen vascular diseases etc. Pulmonary sequestration may present as a mass or with high output failure due to (L)-(R) shunt. Sequestration represents a segment of lung with no developmental connection with tracheobronchial tree. This is a part of bronchopulmonary foregut malformation. Extralobar sequestrations contained in a separate pleural envelope (60% are seen in children <1 year of age ) are more common in a child. Diaphragmatic hernia & congenital heart disease are other associated abnormalities.

Figure 10: Extralobar sequestration




Contributor Information and Disclosures

Priya Chudgar
Lecturer in Radiology, Department of Radiology, KEM Hospital,Mumbai, India


First Created : 1/4/2001

References

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