POLYURIA
Last Updated : 1/2/2009
Kumud P Mehta
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Definition:

Polyuria

is defined as urine output > 2000ml per 1.73M2 /24 hr or more than 2.5-3 ml/kg/24 hrs. Accurate measurement of 24 hours intake of fluids and quantity of urine passed should be done to establish diagnosis of polyuria.

Common causes of polyuria:


- Polydipsia or excessive fluid intake, which can be psychogenic.
- Solute diuresis e.g. glucosuria in diabetes mellitus, calcium in hypercalciuria, sodium chloride in Barter's syndrome and nephronophthisis, sodium bicarbonate in renal tubular acidosis, Fanconi's syndrome or cystinosis.
- Vasopressin or ADH deficiency as in central diabetes insipidus due to hypothalamic or pituitary disorders.
- Resistance to ADH action at the site of renal tubules as in nephrogenic diabetes insipidus
- Chronic renal failure with concentration defect.
- Structural malformations of kidney like obstructive uropathy, hydronephrosis, chronic pyelonephritis with reflux nephropathy etc.



Contributor Information and Disclosures

Kumud P Mehta
Consultant Pediatrician & Pediatric Nephrologist, Jaslok Hospital & Research Centre, Bai Jerbai Wadia Hospital for children, Mumbai, India.


First Created : 1/9/2002

References

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