Last Updated : 1/3/2011
Kumud P Mehta
Renal conditions that can be identified antenatally
Diseases of kidney like hydronephrosis i.e. large kidneys because of dilatation of pelvis, calyces with or without dilatation of ureters due to obstruction at pelviureteral junction or vesicoureteral junction, posterior urethral valves etc can be diagnosed after 18-22 weeks of pregnancy. Complete absence of one or both kidneys i.e. agenesis or small poorly developed kidneys i.e. hypoplastic / dysplastic kidneys can be detected antenatally. Diagnosis of congenital defects of both kidneys like polycystic disease or multicystic disease is also possible.

High risk patients

Renal defects

are common if
- Previous sibling had defects like polycystic kidney disease which is an inherited kidney disease

Other congenital defects

associated affecting the spine, heart, gastrointestinal tract or chromosomal defects
- There is less liquor amnii i.e. oligohydramnios
- Death of previous sibling due to multiple defects
- Elderly mother
- If the marriage is in closely related individuals

Chances of recurrence in future pregnancies
Chances of recurrence in future siblings are high in inherited diseases like Infantile polycystic kidney disease in which each sib has 25% chances of suffering from PKD.

Contributor Information and Disclosures

Kumud P Mehta
Consultant Pediatrician & Pediatric Nephrologist, Jaslok Hospital & Research Centre, Bai Jerbai Wadia Hospital for children.

First Created : 1/5/2001


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