SCRUB TYPHUS
Last Updated : 1/2/2014
Ira Shah
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Scrub typhus

, also called Tsutsugamushi disease, is an acute infectious disease that is transmitted to humans by certain mites (chiggers). Recent outbreaks have been seen in India. The causative organism is Orientia (formerly Rickettsia) tsutsugamushi. Trombiculid mites (Leptotrombidium delinese & L. akamushi) serve as both reservoirs and vectors.

PATHOLOGY


The basic pathologic process of scrub typhus is a perivasculitis of the small blood vessels analogous to the other rickettsial diseases. In addition, an eschar or necrotic inflammatory lesion develops at the site of the mite bite, with subsequent regional lymphadenopathy. General lymphadenopathy occurs commonly in scrub typhus but rarely or not at all in all other rickettsial diseases.

References

Contributor Information and Disclosures

Ira Shah
Consultant Pediatrician and Pediatric Infectious Diseases, Nanavati Hospital, Mumbai, India


First Created : 1/2/2013

References

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