URTICARIA (HIVES) AND ANGIOEDEMA
Last Updated : 1/3/2013
Ira Shah
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Urticaria

is an itchy rash associated with localized swelling (wheals) on the skin that usually lasts for few hours to days before fading away. It is also known as hives.




What is the

cause of Urticaria

?

Acute urticaria is caused by drugs (pain killers such as aspirin, codeine, indomethacin and antibiotics such as penicillin & sulpha), specific food (nuts, eggs, fresh fruits, chocolates, fish, tomatoes, milk, spices, cheese, yeasts, food additives such as yellow dye) or a viral infection. In some cases, no cause can be detected.

Recurrent attacks of urticaria can occur by exposure to environmental agents such as sunlight, cold, pressure and sweat.

Chronic urticaria is defined as hives lasting longer than six weeks. It is rarely due to an allergy. Usually no cause is detected though; 30-40% of patients with chronic idiopathic urticaria will have an autoimmune cause.

What happens in Urticaria?
There is secretion of histamine and other substances from cells in the body leading to itching and enlargement of blood vessel in the skin leading to fluid extravasation and swellings.

Can Urticaria persist?
Acute urticaria resolves in few hours to days. Sometimes urticaria may occur daily and last more than two months. In majority of cases of chronic urticaria, the cause is not known. However, emotional stress is known to aggravate chronic urticaria. Most of the cases of chronic urticaria resolve by about 6 months.



Contributor Information and Disclosures

Ira Shah
Consultant Pediatrician, Nanavati Hospital, Mumbai, India


First Created : 1/7/2003

References

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