Poisning Center - Pediatric On Call

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

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Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katiha...

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Calotropis

Calotropis gigantea {akdo, madar} has purple flowers and Calotropis procera has white flowers. They grow in the wild throughout India.
The active principles are uscharin, calotoxin, calactin and calotropin {glycoside}. The milky juice in addition contains trypsin. The leaves and stem when incised yield thick acrid, milky juice.

Route : Ingestion, Contact

Fatal dose : Uncertain

Fatal Period : 6 to 12 hours

Clinical picture : When applied to the skin, it causes redness and vesication. When taken by mouth, the juice produces an acrid, bitter taste, and burning pain in the throat and stomach, salivation, stomatitis, vomiting, diarrhoea, dilated pupils, tetanic convulsions, collapse and death.

Treatment : Stomach wash, demulcents and symptomatic treatment.

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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?

No, it should be used only after drug sensitivity report

Yes, under guidance of an infectious disease expert

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