4th Pediatric Infectious Diseases Conference

 
 
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POISIONING CENTER
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FIND DIAGNOSIS
FIND DIAGNOSIS
FIND DIAGNOSIS
POISIONING CENTER
 
Pyrethrins and pyrethroids
 
They are extracted from chrysanthemum plant and used as insect repellants and pesticides. They are available as sprays, dusts, powders and mats

Route : Ingestion, inhalation, skin contact

Fatal dose : 1gm/kg body weight

Fatal Period : 2 to 5 days

Mechanism of action : They prolong the inactivation of sodium channel by binding it in the inactive state

Clinical picture : •Skin contact causes dermatitis and blistering
•Paraesthesias, nausea, vomiting, and diarrhea
•Inhalation causes rhinorrhea, sore throat, wheezing and dyspnoea
•Fasciculations, hyperthermia, altered mental status
•Convulsions and coma


Treatment : •Gastric lavage with activated charcoal
•Oils and fats to be avoided
•Atropine and oximes are contraindicated
•Skin should be washed


 
 
 
 
Pedi Poll
Today’s Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
 
Educational Section
 
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